Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A6NU
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| Drug Name |
Haloperidol
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| Synonyms |
Haldol; Aloperidin; Serenace; Aloperidol; Eukystol; Brotopon; Einalon S; Ulcolind; Serenase; Uliolind; Serenelfi; Aloperidolo; Vesalium; Halopoidol; Galoperidol; Halojust; Pernox; Mixidol; Halopal; Linton; Sernel; Sernas; Dozic; Aldo; Lealgin compositum; Keselan; Peluces; Bioperidolo; Haldol Solutab; McN-JR-1625; Haloperidolum; Aloperidon; Fortunan; Aloperidolo [DCIT]; Aloperidolo [Italian]; Haloperidolum [INN-Latin]
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| Drug Type |
Small molecular drug
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| Indication | Schizophrenia [ICD-11: 6A20] | Approved | [1] | |
| Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Investigative | [2] | ||
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Formula |
C21H23ClFNO2
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| Canonical SMILES |
C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
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| InChI |
1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
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| InChIKey |
LNEPOXFFQSENCJ-UHFFFAOYSA-N
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| CAS Number |
CAS 52-86-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:5613
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HUMAN opioid receptor sigma 1 (OPRS1) | Target Info | Modulator | [3] |
| HUMAN sigma intracellular receptor 2 (TMEM97) | Target Info | Modulator | [3] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 076035. | |||
| REF 2 | Sigma-1Rs are upregulated via PERK/eIF2/ATF4 pathway and execute protective function in ER stress. Biochem Biophys Res Commun. 2011 Nov 25;415(3):519-25. | |||
| REF 3 | A SARS-CoV-2 protein interaction map reveals targets for drug repurposing | |||
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