Drug Information
Drug General Information | Top | |||
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Drug ID |
D0A8OW
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Former ID |
DNC009188
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Drug Name |
Subersic acid
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Synonyms |
(+)-subersic acid; CHEMBL455101; CHEBI:66532; 4-hydroxy-3-{(2E)-3-methyl-5-[(4aS,8aS)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]pent-2-en-1-yl}benzoic acid; BDBM50242189
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C26H34O3
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Canonical SMILES |
CC1(CCCC2(C1CCC3=C2CCC(=CCC4=C(C=CC(=C4)C(=O)O)O)C3)C)C
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InChI |
1S/C26H34O3/c1-25(2)13-4-14-26(3)21-10-6-17(15-18(21)9-12-23(25)26)5-7-19-16-20(24(28)29)8-11-22(19)27/h5,8,11,16,23,27H,4,6-7,9-10,12-15H2,1-3H3,(H,28,29)/b17-5-/t23-,26+/m1/s1
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InChIKey |
DJADSIGWJIXULZ-IJOJHBLOSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] |
BioCyc | Resolvin D biosynthesis | |||
Lipoxin biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Linoleic acid metabolism | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
Pathway Interaction Database | IL4-mediated signaling events | |||
WikiPathways | Arachidonic acid metabolism | |||
Eicosanoid Synthesis |
References | Top | |||
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REF 1 | Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. J Nat Prod. 2003 Feb;66(2):230-5. |
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