Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A9CY
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| Former ID |
DIB010685
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| Drug Name |
Pentisomide
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| Synonyms |
Penticainide; Propisomide; ME 3202; CM-7857
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| Drug Type |
Small molecular drug
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| Indication | Heart arrhythmia [ICD-11: BC65; ICD-10: I49, I49.8] | Discontinued in Phase 2 | [1] | |
| Company |
Sanofi
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H33N3O
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| Canonical SMILES |
CC(C)CC(CCN(C(C)C)C(C)C)(C1=CC=CC=N1)C(=O)N
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| InChI |
1S/C19H33N3O/c1-14(2)13-19(18(20)23,17-9-7-8-11-21-17)10-12-22(15(3)4)16(5)6/h7-9,11,14-16H,10,12-13H2,1-6H3,(H2,20,23)
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| InChIKey |
ZZOZYGHXNQPIPS-UHFFFAOYSA-N
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| CAS Number |
CAS 78833-03-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000271) | |||
| REF 2 | Antiarrhythmic effect related to the plasma concentration of pentisomide in vivo and the antiarrhythmic-concentration relationship in vitro. Drugs Exp Clin Res. 1995;21(4):145-51. | |||
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