Drug Information
Drug General Information | Top | |||
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Drug ID |
D0AR4P
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Former ID |
DNC012432
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Drug Name |
2-(9-Benzyl-9H-purin-6-ylamino)-ethanol
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Synonyms |
MLS000083858; AC1LDHLL; CHEMBL7291; MolPort-002-645-925; HMS2407L21; ZINC2352774; STL140995; AKOS005714812; MCULE-9452123598; 2-[(9-benzylpurin-6-yl)amino]ethanol; SMR000048556; 112089-01-7
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H15N5O
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Canonical SMILES |
C1=CC=C(C=C1)CN2C=NC3=C(N=CN=C32)NCCO
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InChI |
1S/C14H15N5O/c20-7-6-15-13-12-14(17-9-16-13)19(10-18-12)8-11-4-2-1-3-5-11/h1-5,9-10,20H,6-8H2,(H,15,16,17)
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InChIKey |
ZOVSVHTVIDXQPS-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction | ||||
Serotonergic synapse | ||||
Reactome | Ligand-gated ion channel transport | |||
GABA A receptor activation | ||||
WikiPathways | SIDS Susceptibility Pathways | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Iron uptake and transport |
References | Top | |||
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REF 1 | Benzodiazepine receptor binding activity of 6,9-disubstituted purines. J Med Chem. 1989 May;32(5):1020-4. |
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