Drug Information
Drug General Information | Top | |||
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Drug ID |
D0AX4E
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Former ID |
DIB008591
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Drug Name |
Bertosamil
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Synonyms |
Bertosamil; 126825-36-3; SCHEMBL379798; CHEMBL2104579; AOIVZQPSIHOHMP-HDICACEKSA-N
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Drug Type |
Small molecular drug
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Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Terminated | [1] | |
Company |
Solvay Pharmaceuticals GmbH
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Structure |
Download2D MOL |
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Formula |
C19H36N2
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Canonical SMILES |
CC(C)CN1CC2CN(CC(C1)C23CCCCC3)C(C)C
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InChI |
1S/C19H36N2/c1-15(2)10-20-11-17-13-21(16(3)4)14-18(12-20)19(17)8-6-5-7-9-19/h15-18H,5-14H2,1-4H3/t17-,18-/m0/s1
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InChIKey |
AOIVZQPSIHOHMP-ROUUACIJSA-N
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CAS Number |
CAS 126825-36-3
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated potassium channel Kv11.1 (KCNH2) | Target Info | Modulator | [1] |
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | Voltage gated Potassium channels | |||
WikiPathways | SIDS Susceptibility Pathways | |||
Hematopoietic Stem Cell Differentiation | ||||
Potassium Channels |
References | Top | |||
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REF 1 | Bertosamil blocks HERG potassium channels in their open and inactivated states. Br J Pharmacol. 2002 Sep;137(2):221-8. |
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