Drug Information
Drug General Information | Top | |||
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Drug ID |
D0B1IC
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Former ID |
DIB007423
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Drug Name |
CR8020
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Synonyms |
H3N2 and H7N7 influenza monoclonal antibody therapy, Crucell
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Drug Type |
Antibody
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Indication | Influenza virus infection [ICD-11: 1E30-1E32] | Phase 2 | [1] | |
Influenza A virus infection [ICD-11: 1E30] | Investigative | [2] | ||
Company |
Crucell
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Target and Pathway | Top | |||
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Target(s) | Influenza Hemagglutinin (Influ HA) | Target Info | . | [3] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01992276) Assessment of Efficacy of CR8020 and CR6261, Monoclonal Antibodies, Against Influenza Infection. U.S. National Institutes of Health. | |||
REF 2 | The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954. | |||
REF 3 | Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin. J Virol. 2014 Dec;88(23):13580-92. |
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