Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B1KK
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| Former ID |
DCL000451
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| Drug Name |
AZD0837
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| Synonyms |
Atecegatran metoxil; Atecegatran fexenetil; UNII-4GU1D587JV; 4GU1D587JV; AZD0837; AZD 0837; 433937-93-0; Atecegatran metoxil [INN]; Atecegatran fexenetil [INN]; SCHEMBL9914214; DB12507; 2-Azetidinecarboxamide, 1-((2R)-(3-chloro-5- (difluoromethoxy)phenyl)hydroxyacetyl)-N-((4-(imino(methoxyamino)methyl)phenyl)methyl)-, (2S)-
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| Drug Type |
Small molecular drug
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| Indication | Nonvalvular atrial fibrillation [ICD-11: BC81.3Y] | Discontinued in Phase 2 | [1], [2] | |
| Thrombosis [ICD-11: DB61-GB90] | Discontinued in Phase 2 | [1], [2] | ||
| Company |
AstraZeneca
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H23ClF2N4O5
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| Canonical SMILES |
CON=C(C1=CC=C(C=C1)CNC(=O)C2CCN2C(=O)C(C3=CC(=CC(=C3)Cl)OC(F)F)O)N
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| InChI |
1S/C22H23ClF2N4O5/c1-33-28-19(26)13-4-2-12(3-5-13)11-27-20(31)17-6-7-29(17)21(32)18(30)14-8-15(23)10-16(9-14)34-22(24)25/h2-5,8-10,17-18,22,30H,6-7,11H2,1H3,(H2,26,28)(H,27,31)/t17-,18+/m0/s1
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| InChIKey |
XSNMGLZVFNDDPW-ZWKOTPCHSA-N
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| CAS Number |
CAS 433937-93-0
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7682). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018351) | |||
| REF 3 | Clinical pipeline report, company report or official report of AstraZeneca (2009). | |||
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