Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B2AH
|
|||
| Former ID |
DNC000571
|
|||
| Drug Name |
DMP-695/696
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Depression [ICD-11: 6A70-6A7Z; ICD-9: 311] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H21Cl2N5O2
|
|||
| Canonical SMILES |
CC1=NN2C(=C1C3=CC(=CC(=C3)Cl)Cl)N=C(N=C2NC(COC)COC)C
|
|||
| InChI |
1S/C18H21Cl2N5O2/c1-10-16(12-5-13(19)7-14(20)6-12)17-21-11(2)22-18(25(17)24-10)23-15(8-26-3)9-27-4/h5-7,15H,8-9H2,1-4H3,(H,21,22,23)
|
|||
| InChIKey |
RHSNHBGJLLYGNA-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticotropin-releasing factor receptor 1 (CRHR1) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Long-term depression | ||||
| NetPath Pathway | TNFalpha Signaling Pathway | |||
| Panther Pathway | Cortocotropin releasing factor receptor signaling pathway | |||
| Reactome | Class B/2 (Secretin family receptors) | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class B Secretin-like | |||
| Myometrial Relaxation and Contraction Pathways | ||||
| Corticotropin-releasing hormone | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A review of drug options in age-related macular degeneration therapy and potential new agents. Expert Opin Pharmacother. 2006 Dec;7(17):2355-68. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.