Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0B4SJ
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| Former ID |
DNC001505
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| Drug Name |
VRC3375
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| Synonyms |
VRC3375; AC1LAH4D; CTK6D4143; tert-butyl 1-{(2r)-2-[2-(hydroxyamino)-2-oxoethyl]hexanoyl}-l-prolinate; tert-butyl (2S)-1-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]hexanoyl]pyrrolidine-2-carboxylate; 1-[(R)-2-[2-Oxo-2-(hydroxyamino)ethyl]hexanoyl]-L-proline tert-butyl ester; L-Proline, 1-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-1-oxohexyl]-, 1,1-dimethylethyl ester; tert-butyl (2S)-1-[(2R)-2-[2-(hydroxyamino)-2-oxo-ethyl]hexanoyl]pyrrolidine-2-carboxylate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H30N2O5
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| Canonical SMILES |
CCCCC(CC(=O)NO)C(=O)N1CCCC1C(=O)OC(C)(C)C
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| InChI |
1S/C17H30N2O5/c1-5-6-8-12(11-14(20)18-23)15(21)19-10-7-9-13(19)16(22)24-17(2,3)4/h12-13,23H,5-11H2,1-4H3,(H,18,20)/t12-,13+/m1/s1
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| InChIKey |
XNOOIEVKOZAJEO-OLZOCXBDSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Staphylococcus Peptide deformylase (Stap-coc def) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach. Antimicrob Agents Chemother. 2004 Jan;48(1):250-61. | |||
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