Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0B5FC
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| Former ID |
DNC001399
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| Drug Name |
T0901317
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| Synonyms |
T0901317; 293754-55-9; T 0901317; TO-901317; TO901317; UNII-A07663A39I; T-0901317; CHEMBL62136; N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide; A07663A39I; N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE; N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide; T-1317
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H12F9NO3S
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| Canonical SMILES |
C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
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| InChI |
1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
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| InChIKey |
SGIWFELWJPNFDH-UHFFFAOYSA-N
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| CAS Number |
CAS 293754-55-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
584397, 584398, 829755, 833311, 7885318, 10300134, 14932512, 17396620, 22394972, 24900032, 26754513, 26759599, 29215533, 36889925, 46519988, 53790753, 56310912, 56464500, 57404841, 74809423, 85257301, 85788194, 87550969, 91722476, 99443551, 99495594, 103249306, 104638688, 124892235, 125334733, 134340458, 134340586, 135334109, 135651223, 135698432, 136946545, 137166930, 142523828, 160968165, 162023380, 163124090, 163687256, 165248887, 172918569, 179317065, 204359633, 208011887, 208012095, 208012803, 212344302
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Oxysterols receptor LXR (NR1H) | Target Info | Binder | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2755). | |||
| REF 2 | The LXR ligand T0901317 induces severe lipogenesis in the db/db diabetic mouse. J Lipid Res. 2003 Nov;44(11):2039-48. | |||
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