Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B6ER
|
|||
| Former ID |
DIB010781
|
|||
| Drug Name |
Ro-31-6930
|
|||
| Synonyms |
Ro-31-6930; 120280-37-7; 2H-1-Benzopyran-6-carbonitrile,2,2-dimethyl-4-(1-oxido-2-pyridinyl)-; Ro 31-6930; ACMC-20motq; AC1MI1CT; CHEMBL97196; SCHEMBL6369348; CTK4B1782; DTXSID70152787; PQVILGHAVGQHRP-UHFFFAOYSA-N; 2-(6-cyano-2,2-dimethyl-2H1-benzopyran-4-yl)pyridine N-oxide; 2,2-dimethyl-4-(1-oxidopyridin-1-ium-2-yl)chromene-6-carbonitrile; 2-(6-cyano-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine 1-oxide; 2-(6-cyano-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Discontinued in Phase 1 | [1] | |
| Company |
Roche Holding AG
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C17H14N2O2
|
|||
| Canonical SMILES |
CC1(C=C(C2=C(O1)C=CC(=C2)C#N)C3=CC=CC=[N+]3[O-])C
|
|||
| InChI |
1S/C17H14N2O2/c1-17(2)10-14(15-5-3-4-8-19(15)20)13-9-12(11-18)6-7-16(13)21-17/h3-10H,1-2H3
|
|||
| InChIKey |
PQVILGHAVGQHRP-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 120280-37-7
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000054) | |||
| REF 2 | Evaluation of the bronchodilator properties of Ro 31-6930, a novel potassium channel opener, in the guinea-pig. Br J Pharmacol. 1990 Jun;100(2):289-94. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.