Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0B8ZP
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| Drug Name |
PD-144418
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| Synonyms |
PD144418; PD 144418; ZINC5862; GTPL10731; BDBM50251208; AKOS024457192; NCGC00378668-01; HY-108512; CS-0029071; Q27456166
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| Drug Type |
Small molecular drug
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| Indication | Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Investigative | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Formula |
C18H22N2O
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| Canonical SMILES |
CCCN1CCC=C(C1)C2=CC(=NO2)C3=CC=C(C=C3)C
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| InChI |
1S/C18H22N2O/c1-3-10-20-11-4-5-16(13-20)18-12-17(19-21-18)15-8-6-14(2)7-9-15/h5-9,12H,3-4,10-11,13H2,1-2H3
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| InChIKey |
FOQRKFCLRMMKAT-UHFFFAOYSA-N
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| CAS Number |
CAS 154130-99-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HUMAN opioid receptor sigma 1 (OPRS1) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The pharmacology of the novel and selective sigma ligand, PD 144418. Neuropharmacology. 1997 Jan;36(1):51-62. | |||
| REF 2 | A SARS-CoV-2 protein interaction map reveals targets for drug repurposing | |||
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