Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0B9IX
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| Former ID |
DNC013730
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| Drug Name |
1-(3-Phenylallylidene)thiosemicarbazide
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| Synonyms |
Cinnamaldehyde thiosemicarbazone; CHEMBL388025; 5351-70-2; 1-(3-Phenylallylidene)thiosemicarbazide; AC1NVG31; Cinnamaldehydethiosemicarbazone; 3-Phenylpropenalthiosemicarbazone; BDBM50241213; ZINC11536050; 3-phenylacrylaldehyde thiosemicarbazone; AKOS023092594; (Z)-1-((E)-3-phenylallylidene)thiosemicarbazide; AF-960/00472016; [(Z)-[(E)-3-phenylprop-2-enylidene]amino]thiourea; F3111-2831; N'-[(3-phenylprop-2-en-1-ylidene)amino]carbamimidothioic acid; (1Z,N'Z)-N'-((E)-3-phenylallylidene)carbamohydrazonothioic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H11N3S
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| Canonical SMILES |
C1=CC=C(C=C1)C=CC=NNC(=S)N
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| InChI |
1S/C10H11N3S/c11-10(14)13-12-8-4-7-9-5-2-1-3-6-9/h1-8H,(H3,11,13,14)/b7-4+,12-8-
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| InChIKey |
SHUQFXIRXYXNOZ-JHLWKMQHSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A class of potent tyrosinase inhibitors: alkylidenethiosemicarbazide compounds. Eur J Med Chem. 2009 Apr;44(4):1773-8. | |||
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