Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0BK4X
|
|||
| Former ID |
DAP001545
|
|||
| Drug Name |
Cinryze
|
|||
| Indication | Hereditary angioedema [ICD-11: 4A00.14; ICD-9: 277.6] | Approved | [1] | |
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | C1 esterase inhibitor (SERPING1) | Target Info | Modulator | [2] |
| Complement C1s component (C1S) | Target Info | Modulator | [2] | |
| KEGG Pathway | Complement and coagulation cascades | |||
| Pertussis | ||||
| Staphylococcus aureus infection | ||||
| Systemic lupus erythematosus | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| WikiPathways | Complement and Coagulation Cascades | |||
| Complement Activation, Classical Pathway | ||||
| Human Complement System | ||||
| Complement cascade | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drug candidates of dipeptidyl peptidase IV (DPP IV) inhibitor class for the treatment of Type 2 Diabetes. Curr Drug Targets. 2009 Jan;10(1):71-87. | |||
| REF 2 | 2008 FDA drug approvals. Nat Rev Drug Discov. 2009 Feb;8(2):93-6. | |||
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