Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0BT1A
|
|||
| Former ID |
DIB018576
|
|||
| Drug Name |
2-pyridylethylamine
|
|||
| Synonyms |
2-(2-Aminoethyl)pyridine; 2706-56-1; 2-Pyridylethylamine; 2-(pyridin-2-yl)ethanamine; 2-(2-Pyridyl)ethylamine; 2-Pyridineethanamine; 2-pyridin-2-ylethanamine; Demethylbetahistine; alpha-Pyridylethylamine; 2-(pyridin-2-yl)ethan-1-amine; Lilly 04432; Pyridine, 2-(2-aminoethyl)-; UNII-ATW1AH7OJ5; Pyridineethanamine; 2-(2'-Aminoethyl)pyridine; NSC 71989; .alpha.-Pyridylethylamine; EINECS 220-295-1; ATW1AH7OJ5; 2-AMINOETHYLPYRIDINE; 2-(2-Pyridinyl)ethanamine; 2-(2-aminoethyl)-pyridine; 2-(2-aminoethyl) pyridine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C7H10N2
|
|||
| Canonical SMILES |
C1=CC=NC(=C1)CCN
|
|||
| InChI |
1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2
|
|||
| InChIKey |
XPQIPUZPSLAZDV-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 2706-56-1
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
114838, 3131926, 4760914, 8139935, 8197638, 10516442, 15194427, 24890987, 29215556, 33239118, 43131639, 46386941, 47217226, 47885859, 48415388, 49681778, 49846679, 50068746, 51072144, 57319844, 57566665, 57641336, 80200244, 84974739, 85173768, 85177265, 85208914, 85787663, 87559237, 87691264, 88809650, 92136720, 92308472, 92714356, 103122164, 103207571, 104362959, 104668887, 117521967, 117531357, 117531392, 117651842, 117687086, 118284203, 121280609, 124659053, 125346668, 126588407, 126610912, 126624200
|
|||
| ChEBI ID |
CHEBI:74024
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H1 receptor (H1R) | Target Info | Agonist | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | Histamine H1 receptor mediated signaling pathway | |||
| Reactome | Histamine receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| IL-4 Signaling Pathway | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1197). | |||
| REF 2 | Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor. Eur J Biochem. 2004 Jul;271(13):2636-46. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.