Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C0PL
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| Former ID |
DNC012513
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| Drug Name |
PT-115
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| Synonyms |
149488-76-6; Thiourea, N-(5-bromo-2-pyridinyl)-N'-(2-(2,6-difluoro-3-methoxyphenyl)ethyl)-; 1-(5-bromopyridin-2-yl)-3-[2-(2,6-difluoro-3-methoxyphenyl)ethyl]thiourea; N-(2-(2,6-Difluoro-3-methoxyphenethyl))-N'-(2-(5-bromopyridyl))thiourea; N-[2-(2,6-Difluoro-3-methoxyphenethyl)]-N'-[2-(5-bromopyridyl)]thiourea; Thiourea, N-(5-bromo-2-pyridinyl)-N'-[2-(2,6-difluoro-3-methoxyphenyl)ethyl]-; PT-115; AC1MHDLW; LY300046HCl Analog 7; SCHEMBL6963627; CHEMBL398890; BDBM2123; DTXSID50164323
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H14BrF2N3OS
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| Canonical SMILES |
COC1=C(C(=C(C=C1)F)CCNC(=S)NC2=NC=C(C=C2)Br)F
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| InChI |
1S/C15H14BrF2N3OS/c1-22-12-4-3-11(17)10(14(12)18)6-7-19-15(23)21-13-5-2-9(16)8-20-13/h2-5,8H,6-7H2,1H3,(H2,19,20,21,23)
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| InChIKey |
HINMFTUIHCBZCY-UHFFFAOYSA-N
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| CAS Number |
CAS 149488-76-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Inhibitor | [1] |
| References | Top | |||
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| REF 1 | Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity r... J Med Chem. 1996 Oct 11;39(21):4261-74. | |||
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