Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C2FS
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| Former ID |
DNC003944
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| Drug Name |
2-(2-Mercapto-ethyl)-pentanedioic acid
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| Synonyms |
2-(2-sulfanylethyl)pentanedioic Acid; CHEMBL292562; 254737-18-3; Pentanedioic acid, 2-(2-mercaptoethyl)-; 2-(2-Mercapto-ethyl)-pentanedioic acid; SCHEMBL2058227; CTK0J4031; DTXSID80430765; SMGZBRVSYVJHCB-UHFFFAOYSA-N
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H12O4S
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| Canonical SMILES |
C(CC(=O)O)C(CCS)C(=O)O
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| InChI |
1S/C7H12O4S/c8-6(9)2-1-5(3-4-12)7(10)11/h5,12H,1-4H2,(H,8,9)(H,10,11)
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| InChIKey |
SMGZBRVSYVJHCB-UHFFFAOYSA-N
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| CAS Number |
CAS 254737-18-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor. J Med Chem. 2003 May 8;46(10):1989-96. | |||
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