Drug Information
Drug General Information | Top | |||
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Drug ID |
D0C4GN
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Drug Name |
CD33-CAR-T Cell
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Drug Type |
CAR T Cell Therapy
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Indication | Acute myeloid leukaemia [ICD-11: 2A60] | Phase 1 | [1] | |
Haematopoietic/lymphoid cancer [ICD-11: 2B33.5; ICD-10: C85.9] | Phase 1 | [1] | ||
Company |
M.D. Anderson Cancer Center
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Target and Pathway | Top | |||
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Target(s) | Myeloid cell surface antigen CD33 (CD33) | Target Info | CAR-T-Cell-Therapy | [1] |
KEGG Pathway | Hematopoietic cell lineage | |||
Reactome | Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT03126864) Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia |
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