Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C7GB
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| Former ID |
DNC013011
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| Drug Name |
1-(piperidin-3-ylmethyl)pyridin-2(1H)-one
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| Synonyms |
1-(piperidin-3-ylmethyl)pyridin-2(1H)-one; 820231-74-1; 2(1H)-Pyridinone, 1-(3-piperidinylmethyl)-; CHEMBL205267; SCHEMBL2503319; CTK3E3069; DTXSID80658785; CRXGPVZZFUWGAF-UHFFFAOYSA-N; AKOS010944098; 1-Piperidin-3-ylmethyl-1H-pyridin-2-one; 1-[(Piperidin-3-yl)methyl]pyridin-2(1H)-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H16N2O
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| Canonical SMILES |
C1CC(CNC1)CN2C=CC=CC2=O
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| InChI |
1S/C11H16N2O/c14-11-5-1-2-7-13(11)9-10-4-3-6-12-8-10/h1-2,5,7,10,12H,3-4,6,8-9H2
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| InChIKey |
CRXGPVZZFUWGAF-UHFFFAOYSA-N
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| CAS Number |
CAS 820231-74-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-2 (CHRNA2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
| Reactome | Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | |||
| Highly calcium permeable nicotinic acetylcholine receptors | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity. J Med Chem. 2006 May 4;49(9):2673-6. | |||
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