Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0C8DC
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| Former ID |
DIB014271
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| Drug Name |
Ki-1769
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| Synonyms |
Ki-1769; Ki 1769; AC1L2ZHG; ki1769; SCHEMBL9214494; SCHEMBL6377119; CHEMBL310746; SUPZSNPDPSPMTK-UHFFFAOYSA-N; N-CYANO-N'-(2-PHENYLETHYL)-3-PYRIDINECARBOXIMIDAMIDE; N-cyano-N'-phenethylpyridine-3-carboximidamide; 3-Pyridinecarboximidamide, N-cyano-N'-(2-phenylethyl)-
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Terminated | [1] | |
| Company |
Kirin Brewery Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C15H14N4
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| Canonical SMILES |
C1=CC=C(C=C1)CCN=C(C2=CN=CC=C2)NC#N
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| InChI |
1S/C15H14N4/c16-12-19-15(14-7-4-9-17-11-14)18-10-8-13-5-2-1-3-6-13/h1-7,9,11H,8,10H2,(H,18,19)
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| InChIKey |
SUPZSNPDPSPMTK-UHFFFAOYSA-N
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| CAS Number |
CAS 133300-00-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002625) | |||
| REF 2 | Vasorelaxant action of Ki1769, a new pyridinecarboximidamide, in isolated porcine coronary artery. Eur J Pharmacol. 1993 Sep 14;241(2-3):177-81. | |||
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