Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0C8IB
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| Former ID |
DNC010645
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| Drug Name |
(R)-3-(1H-imidazol-4-yl)propyl sec-butylcarbamate
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| Synonyms |
CHEMBL1080089; BDBM50311765; BDBM50074071; [(1R)-1-Methylpropyl]carbamic acid 3-(1H-imidazole-4-yl)propyl ester; ((R)-sec-Butyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H19N3O2
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| Canonical SMILES |
CCC(C)NC(=O)OCCCC1=CN=CN1
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| InChI |
1S/C11H19N3O2/c1-3-9(2)14-11(15)16-6-4-5-10-7-12-8-13-10/h7-9H,3-6H2,1-2H3,(H,12,13)(H,14,15)/t9-/m1/s1
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| InChIKey |
RSHJCGZZSGNBHO-SECBINFHSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| Histamine H4 receptor (H4R) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6682-5. | |||
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