Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D1TS
|
|||
| Drug Name |
Isoquinoline derivative 2
|
|||
| Synonyms |
PMID27215781-Compound-23
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Neuropathic pain [ICD-11: 8E43.0] | Patented | [1] | |
| Company |
LUPIN LIMITED KULKARNI, Sanjeev, Anant MADAN, Sachin JANA, Nirmal, Kumar TALE, Prashant, Vitthalrao CHEEMALA, Narasimha, Murthy MAHANGARE, Sachin, Jaysing VIDHATE, Prashant, Popatrao KULKARNI, Chaitanya, Prabhakar PATEL, Sapana, Suresh PATIL, Amolsing, Dattu ZADE, Seema, Prabhakar SHINDE, Rohan, Mahadev PALLE, Venkata, P. KAMBOJ, Rajender, KumaLUPIN LIMITED KULKARNI, Sanjeev, Anant MADAN, Sachin JANA, Nirmal, Kumar MAHANGARE, Sachin, Jaysing TALE, Prashant, Vitthalrao ZADE, Seema, Prabhakar PATIL, Amolsing, Dattu CHEEMALA, Narasimha, Murthy PALLE, Venkata, P. KAMBOJ, Rajender, KumaLUPIN LIMITED KULKARNI, Sanjeev, Anant MADAN, Sachin JANA, Nirmal, Kumar TALE, Prashant, Vitthalrao CHEEMALA, Narasimha, Murthy MAHANGARE, Sachin, Jaysing VIDHATE, Prashant, Popatrao KULKARNI, Chaitanya, Prabhakar PATEL, Sapana, Suresh PATIL, Amolsing, Dattu SHINDE, Rohan, Mahadev PALLE, Venkata, P. KAMBOJ, Rajender, Kumar
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H20FN3O2
|
|||
| Canonical SMILES |
CC1=C2C(=CC=C1)C(=NC=C2C(=O)N3CCOCC3)NC4=CC(=CC=C4)F
|
|||
| InChI |
1S/C21H20FN3O2/c1-14-4-2-7-17-19(14)18(21(26)25-8-10-27-11-9-25)13-23-20(17)24-16-6-3-5-15(22)12-16/h2-7,12-13H,8-11H2,1H3,(H,23,24)
|
|||
| InChIKey |
QKTNWXFWLOHPFJ-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 2 (CB2) | Target Info | . | [1] |
| Target's Patent Info | Cannabinoid receptor 2 (CB2) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cannabinoid receptor 2 (CB2) agonists and antagonists: a patent update.Expert Opin Ther Pat. 2016 Jul;26(7):843-56. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.