Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D5XX
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| Former ID |
DIB020673
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| Drug Name |
peptide 4
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| Synonyms |
CHEMBL263633; GTPL8582; BDBM50376756; peptide 4 [PMID: 18294843]; (2S)-2-[[(2S)-2-[2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]prop-2-enoylamino]-3-methylbutanoyl]amino]propanoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL
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| Formula |
C20H36N8O6
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| Canonical SMILES |
CC(C)C(C(=O)NC(C)C(=O)O)NC(=O)C(=C)NC(=O)C(C)NC(=O)C(CCCN=C(N)N)N
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| InChI |
1S/C20H36N8O6/c1-9(2)14(18(32)27-12(5)19(33)34)28-16(30)11(4)25-15(29)10(3)26-17(31)13(21)7-6-8-24-20(22)23/h9-10,12-14H,4,6-8,21H2,1-3,5H3,(H,25,29)(H,26,31)(H,27,32)(H,28,30)(H,33,34)(H4,22,23,24)/t10-,12-,13-,14-/m0/s1
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| InChIKey |
VZQHRKZCAZCACO-PYJNHQTQSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tripeptidyl-peptidase II (TPP2) | Target Info | Inhibitor | [1] |
| Reactome | Antigen processing: Ubiquitination & Proteasome degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Use of lantibiotic synthetases for the preparation of bioactive constrained peptides. Bioorg Med Chem Lett. 2008 May 15;18(10):3025-8. | |||
| REF 2 | Structure and function of tripeptidyl peptidase II, a giant cytosolic protease. Biochim Biophys Acta. 2012 Jan;1824(1):237-45. | |||
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