Drug Information
Drug General Information | Top | |||
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Drug ID |
D0D7YL
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Former ID |
DNC006003
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Drug Name |
3-(1,2-dihydroacenaphthylen-3-yl)pyridine
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Synonyms |
acenaphthene derivative A; 3-(1,2-dihydroacenaphthylen-3-yl)pyridine; CHEMBL372747; SCHEMBL4225082
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C17H13N
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Canonical SMILES |
C1CC2=C(C=CC3=C2C1=CC=C3)C4=CN=CC=C4
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InChI |
1S/C17H13N/c1-3-12-6-8-15(14-5-2-10-18-11-14)16-9-7-13(4-1)17(12)16/h1-6,8,10-11H,7,9H2
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InChIKey |
CKORXOPHZBFEPV-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | Development and evaluation of a pharmacophore model for inhibitors of aldosterone synthase (CYP11B2). Bioorg Med Chem Lett. 2006 Jan 1;16(1):25-30. |
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