Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0D8VE
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| Former ID |
DAP000692
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| Drug Name |
Halothane
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| Synonyms |
Alotano; Anestan; Bromchlortrifluoraethanum; Bromochlorotrifluoroethane; Chalothane; Fluktan; Fluorotane; Fluothane; Ftorotan; Ftuorotan; Halan; Halotan; Halotano; Halothan; Halothanum; Halsan; Narcotan; Narcotane; Narkotan; Phthorothanum; Rhodialothan; Alotano [DCIT]; Ftorotan [Russian]; CF3CHClBr; Freon 123B1; Fluothane (TN); Halotano [INN-Spanish]; Halothane [Anaesthetics, volatile]; Halothanum [INN-Latin]; Narcotann NE-spofa [Russian]; Narcotann ne-spofa; Halothane [INN:BAN:JAN]; Halothane (JP15/USP/INN); (+-)-2-Bromo-2-chloro-1,1,1-trifluoroethane; 1,1,1-Trifluoro-2-bromo-2-chloroethane; 1,1,1-Trifluoro-2-chloro-2-bromoethane; 1-Bromo-1-chloro-2,2,2-trifluoroethane; 2,2,2-Trifluoro-1-chloro-1-bromoethane; 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE; 2-Brom-2-chlor-1,1,1-trifluorethan
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1], [2] | |
| Therapeutic Class |
Anesthetics
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| Structure |
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Download2D MOL |
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| Formula |
C2HBrClF3
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| Canonical SMILES |
C(C(F)(F)F)(Cl)Br
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| InChI |
1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H
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| InChIKey |
BCQZXOMGPXTTIC-UHFFFAOYSA-N
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| CAS Number |
CAS 151-67-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9718, 428040, 3159200, 5123763, 7847608, 7979527, 8145848, 8152252, 10508848, 15067445, 17388981, 24850204, 24891772, 29222693, 46506589, 48423484, 48425179, 49855046, 53790292, 56311498, 56311785, 56311842, 56311861, 56313444, 56313445, 56313447, 57321872, 76126220, 92308210, 103242558, 104006665, 104303878, 114917783, 124890113, 124890114, 125539176, 126677461, 127269303, 127269304, 127269305, 127269306, 127269307, 127269308, 127269309, 127269310, 127269311, 127269312, 127269313, 127269314, 127269315
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| ChEBI ID |
CHEBI:5615
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| ADReCS Drug ID | BADD_D01057 | |||
| SuperDrug ATC ID |
N01AB01
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| SuperDrug CAS ID |
cas=000151677
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Antagonist | [3] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2401). | |||
| REF 2 | Benzodiazepine utilisation in Australia: report from a new pharmacoepidemiological database. Aust J Public Health. 1993 Dec;17(4):345-9. | |||
| REF 3 | Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK-1. Br J Pharmacol. 2007 Nov;152(6):939-45. | |||
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