Drug Information
Drug General Information | Top | |||
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Drug ID |
D0D9CO
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Former ID |
DNC001580
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Drug Name |
SB-221420-A
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Synonyms |
SB-221420-A
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Drug Type |
Small molecular drug
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Indication | Pain [ICD-11: MG30-MG3Z] | Investigative | [1] | |
Therapeutic Class |
Analgesics
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Structure |
Download2D MOL |
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Formula |
C25H28ClNO
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Canonical SMILES |
CC(C)(C1=CC=CC=C1)C2=CC=C(C=C2)OC3C(CC4=CC=CC=C34)NC.Cl
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InChI |
1S/C25H27NO.ClH/c1-25(2,19-10-5-4-6-11-19)20-13-15-21(16-14-20)27-24-22-12-8-7-9-18(22)17-23(24)26-3;/h4-16,23-24,26H,17H2,1-3H3;1H/t23-,24+;/m1./s1
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InChIKey |
GWFDWCZMDDKZDV-ITNPDYSASA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated sodium channel alpha Nav1.9 (SCN11A) | Target Info | Blocker | [1] |
Reactome | Interaction between L1 and Ankyrins |
References | Top | |||
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REF 1 | Recent updates of N-type calcium channel blockers with therapeutic potential for neuropathic pain and stroke. Curr Top Med Chem. 2009;9(4):377-95. |
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