Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0DF2M
|
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| Drug Name |
PMID28870136-Compound-48
|
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| Drug Type |
Small molecular drug
|
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| Company |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C7H8N4O2
|
|||
| Canonical SMILES |
CN1C2=C(C(=O)N(C1=O)C)NC=N2
|
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| InChI |
1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)
|
|||
| InChIKey |
ZFXYFBGIUFBOJW-UHFFFAOYSA-N
|
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| CAS Number |
CAS 58-55-9
|
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:28177
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ecto-5'-nucleotidase (CD73) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Ecto-5'-nucleotidase (CD73) | Target's Patent Info | [1] | |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Adenosine nucleotides degradation | ||||
| KEGG Pathway | Purine metabolism | |||
| Pyrimidine metabolism | ||||
| Nicotinate and nicotinamide metabolism | ||||
| Metabolic pathways | ||||
| Panther Pathway | Purine metabolism | |||
| Pyrimidine Metabolism | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Purine catabolism | |||
| WikiPathways | Differentiation Pathway | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Metabolism of nucleotides | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304. | |||
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