Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0DZ3X
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| Former ID |
DAP000198
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| Drug Name |
L-Proline
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| Synonyms |
Carboxypyrrolidine; Pro; Prolina; Prolinum; Prolina [Spanish]; Prolinum [Latin]; CB 1707; L-Prolin; PRO (IUPACabbreviation); Proline (USP); Proline (VAN); Proline [USAN:INN]; H-Pro-OH; L-Proline (JAN); L-Proline-15N; L-alpha-Pyrrolidinecarboxylic acid; L-Proline, labeled with carbon-14; L-Pyrrolidine-2-carboxylic acid; L-(2,3-3H)Proline; (-)-(S)-Proline; (-)-2-Pyrrolidinecarboxylic acid; (-)-Proline (S)-2-Carboxypyrrolidine; (2S)-pyrrolidine-2-carboxylic acid; (S)-2-Carboxypyrrolidine; (S)-2-Pyrrolidinecarboxylic acid; (S)-Proline; (S)-Pyrrolidine-2-carboxylic acid; 2-pyrrolidinecarboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Malnutrition [ICD-11: 5B50-5B71] | Approved | [1], [2] | |
| Therapeutic Class |
Dietary supplement
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| Structure |
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Download2D MOL |
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| Formula |
C5H9NO2
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| Canonical SMILES |
C1CC(NC1)C(=O)O
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| InChI |
1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
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| InChIKey |
ONIBWKKTOPOVIA-BYPYZUCNSA-N
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| CAS Number |
CAS 4305-67-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3448, 608065, 838056, 841800, 3135874, 4253464, 6436528, 6436535, 6436537, 7847103, 7887166, 7890050, 8144250, 10248984, 10508477, 14710669, 15146482, 15194368, 17435868, 24882005, 24887885, 24887886, 24898097, 24898677, 24898986, 24901637, 24902491, 41102174, 46223069, 46504839, 46506858, 49856395, 50108816, 57288676, 57346151, 57652885, 57652886, 57654568, 77943168, 81044534, 81067296, 85164895, 85182322, 85201946, 87574669, 92298421, 92710581, 96021916, 96100167, 99206182
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| ChEBI ID |
CHEBI:17203
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3314). | |||
| REF 2 | Escherichia coli cyclophilin B binds a highly distorted form of trans-prolyl peptide isomer. Eur J Biochem. 2004 Sep;271(18):3794-803. | |||
| REF 3 | Mechanistic insight into the role of transition-state stabilization in cyclophilin A. J Am Chem Soc. 2009 Jan 14;131(1):147-52. | |||
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