Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0E4KI
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| Former ID |
DIB019843
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| Drug Name |
example 8 [WO1999033801A1]
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| Synonyms |
example 8 [WO1999033801A1]; GTPL8581
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C15H17F4N3O2
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| Canonical SMILES |
CCC(C(=O)N1C(CC2=C1C=CC=C2F)C(=O)NCC(F)(F)F)N
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| InChI |
1S/C15H17F4N3O2/c1-2-10(20)14(24)22-11-5-3-4-9(16)8(11)6-12(22)13(23)21-7-15(17,18)19/h3-5,10,12H,2,6-7,20H2,1H3,(H,21,23)/t10-,12+/m0/s1
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| InChIKey |
GNYDXSHWPPTVEX-CMPLNLGQSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tripeptidyl-peptidase II (TPP2) | Target Info | Inhibitor | [2] |
| Reactome | Antigen processing: Ubiquitination & Proteasome degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure and function of tripeptidyl peptidase II, a giant cytosolic protease. Biochim Biophys Acta. 2012 Jan;1824(1):237-45. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2423). | |||
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