Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E6KF
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| Drug Name |
Carbamide derivative 2
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| Synonyms |
PMID25470667-Compound-Figure5-19
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| Drug Type |
Small molecular drug
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| Company |
GLAXOSMITHKLINE LLGLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED QIN, Donghui CHEUNG, Mui JOSHI, Hemant TANGIRALA, Raghuram BETHI, Sridhar, Reddy
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| Structure |
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Download2D MOL |
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| Formula |
C27H25F3N4O4
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| Canonical SMILES |
CCC1=CC=C(C=C1)NC(=O)NC2=NC=C(N=C2)C3=CC4=C(C=C3)C(=O)C(CC4)(CC(=O)O)CC(F)(F)F
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| InChI |
1S/C27H25F3N4O4/c1-2-16-3-6-19(7-4-16)33-25(38)34-22-14-31-21(13-32-22)18-5-8-20-17(11-18)9-10-26(24(20)37,12-23(35)36)15-27(28,29)30/h3-8,11,13-14H,2,9-10,12,15H2,1H3,(H,35,36)(H2,32,33,34,38)
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| InChIKey |
YPGWBIYAJJSEDN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 7 receptor (HTR7) | Target Info | Inhibitor | [1] |
| Target's Patent Info | 5-HT 7 receptor (HTR7) | Target's Patent Info | [1] | |
| KEGG Pathway | Ras signaling pathway | |||
| Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | ||||
| Serotonergic synapse | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 7 and Serotonin | |||
| Reactome | Serotonin receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58. | |||
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