Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E6SB
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| Former ID |
DIB013438
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| Drug Name |
HQK-1001
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| Synonyms |
Sodium ST-20; Hematological disease therapeutic (oral), HemaQuest
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| Drug Type |
Small molecular drug
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| Indication | Beta thalassemia [ICD-11: 3A50.2; ICD-10: D56.1, D56.3] | Phase 2 | [1] | |
| Company |
Hemaquest pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C6H11NaO2
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| Canonical SMILES |
CCC(C)(C)C(=O)[O-].[Na+]
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| InChI |
1S/C6H12O2.Na/c1-4-6(2,3)5(7)8;/h4H2,1-3H3,(H,7,8);/q;+1/p-1
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| InChIKey |
OOPXYEYPPHJHSE-UHFFFAOYSA-M
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| CAS Number |
CAS 3934-02-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A phase 2 trial of HQK-1001 in HbE-beta thalassemia demonstrates HbF induction and reduced anemia. Blood. 2014 Mar 20;123(12):1956-7. | |||
| REF 2 | A phase 2 study of HQK-1001, an oral fetal haemoglobin inducer, in beta-thalassaemia intermedia. Br J Haematol. 2014 Feb;164(3):456-8. | |||
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