Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0E6VL
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| Former ID |
DIB016231
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| Drug Name |
RWJ-22108
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| Synonyms |
Rwj-22108; 112769-37-6; 2-(Methyl(phenylmethyl)amino)ethyl 4-(2-chloro-6-fluorophenyl)-1,4,6,7,8,9-hexahydro-2-methylthiepino(3,2-b)pyridine-3-carboxylate 5,5-dioxide; Thiepino[3,2-b]pyridine-3-carboxylicacid, 4-(2-chloro-6-fluorophenyl)-1,4,6,7,8,9-hexahydro-2-methyl-,2-[methyl(phenylmethyl)amino]ethyl ester, 5,5-dioxide; Rwj 22108; ACMC-20cv3e; AC1L4TSX; AC1Q4O13; CTK4A7965
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| Drug Type |
Small molecular drug
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| Indication | Allergy [ICD-11: 4A80-4A85; ICD-10: T78.4; ICD-9: 995.3] | Terminated | [1] | |
| Company |
RW Johnson Pharmaceutical Research Institute
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| Structure |
 |
Download2D MOL |
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| Formula |
C27H30ClFN2O4S
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| Canonical SMILES |
CC1=C(C(C2=C(N1)CCCCS2(=O)=O)C3=C(C=CC=C3Cl)F)C(=O)OCCN(C)CC4=CC=CC=C4
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| InChI |
1S/C27H30ClFN2O4S/c1-18-23(27(32)35-15-14-31(2)17-19-9-4-3-5-10-19)25(24-20(28)11-8-12-21(24)29)26-22(30-18)13-6-7-16-36(26,33)34/h3-5,8-12,25,30H,6-7,13-17H2,1-2H3
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| InChIKey |
AHYGPFWAZFOLSI-UHFFFAOYSA-N
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| CAS Number |
CAS 112769-37-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002359) | |||
| REF 2 | Design and discovery of RWJ 22108--a novel bronchoselective calcium channel blocker. Drug Des Discov. 1998 May;15(3):135-48. | |||
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