Drug Information
Drug General Information | Top | |||
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Drug ID |
D0E8KS
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Former ID |
DNC001279
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Drug Name |
SB 203186
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Synonyms |
SB 203186; SB-203186; 2-piperidin-1-ylethyl 1H-indole-3-carboxylate; Tocris-0785; NCGC00015921-01; Lopac-S-0443; Biomol-NT_000150; AC1MN68M; Lopac0_000347; GTPL255; BPBio1_000617; SCHEMBL1041116; CHEMBL1255781; ZINC14457; CHEBI:92477; BDBM85778; YGKPIROTKVQCCU-UHFFFAOYSA-N; CCG-204442; NCGC00024790-03; NCGC00015921-02; NCGC00024790-01; NCGC00024790-02; NCGC00015921-04; NCGC00015921-03; CAS_135938-17-9; (1-piperidinyl)ethyl 1h-indole 3-carboxylate; 2-(1-piperidyl)ethyl 1H-indole-3-carboxylate; 2-(1-Piperidyl)ethyl 1 H-indole-3-carboxy
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C16H20N2O2
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Canonical SMILES |
C1CCN(CC1)CCOC(=O)C2=CNC3=CC=CC=C32
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InChI |
1S/C16H20N2O2/c19-16(20-11-10-18-8-4-1-5-9-18)14-12-17-15-7-3-2-6-13(14)15/h2-3,6-7,12,17H,1,4-5,8-11H2
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InChIKey |
YGKPIROTKVQCCU-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
4310608, 9251882, 11111770, 11113704, 15221946, 26751893, 34646190, 48018901, 48169370, 48393930, 50104570, 57356138, 77935497, 85213147, 85787316, 111881535, 123084781, 124749640, 124881385, 124881386, 124881387, 129792181, 134340485, 135650982, 136351878, 137031077, 138956298, 225044358, 227291137
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ChEBI ID |
CHEBI:92477
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Target and Pathway | Top | |||
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Target(s) | 5-HT 4 receptor (HTR4) | Target Info | Antagonist | [1] |
KEGG Pathway | Calcium signaling pathway | |||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Serotonergic synapse | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
5HT4 type receptor mediated signaling pathway | ||||
Pathwhiz Pathway | Excitatory Neural Signalling Through 5-HTR 4 and Serotonin | |||
Reactome | Serotonin receptors | |||
G alpha (s) signalling events | ||||
WikiPathways | Serotonin Receptor 4/6/7 and NR3C Signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | 5-Hydroxytryptamine mediated contractions in isolated preparations of equine ileum and pelvic flexure: pharmacological characterization of a new 5-HT(4) agonist. J Vet Pharmacol Ther. 2002 Feb;25(1):49-58. |
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