Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0ER1G
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| Former ID |
DNC012115
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| Drug Name |
4-Hydroxy-piperidine-3-carboxylic acid
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| Synonyms |
CHEMBL277372; SCHEMBL5426302; ZINC26898692; BDBM50223874; AKOS006353852; (3S)-4alpha-Hydroxypiperidine-3alpha-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H11NO3
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| Canonical SMILES |
C1CNCC(C1O)C(=O)O
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| InChI |
1S/C6H11NO3/c8-5-1-2-7-3-4(5)6(9)10/h4-5,7-8H,1-3H2,(H,9,10)/t4-,5+/m0/s1
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| InChIKey |
DAMFVOCECLPLSI-CRCLSJGQSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA transporter GAT-1 (SLC6A1) | Target Info | Inhibitor | [1] |
| GABA transporter-3 (SLC6A11) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | GABAergic synapse | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hydroxy- and amino-substituted piperidinecarboxylic acids as gamma-aminobutyric acid agonists and uptake inhibitors. J Med Chem. 1982 Oct;25(10):1157-62. | |||
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