Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F6VD
|
|||
| Drug Name |
Lactam derivative 1
|
|||
| Synonyms |
PMID25470667-Compound-Figure5-13
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
ASTRAZENECA AB ASTRAZENECA UK LIMITED
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C19H14Cl2N4O2
|
|||
| Canonical SMILES |
C1COC2=NC=NC(=C2C(=O)N1C3=CC=C(C=C3)C4=C(C=C(C=C4)Cl)Cl)N
|
|||
| InChI |
1S/C19H14Cl2N4O2/c20-12-3-6-14(15(21)9-12)11-1-4-13(5-2-11)25-7-8-27-18-16(19(25)26)17(22)23-10-24-18/h1-6,9-10H,7-8H2,(H2,22,23,24)
|
|||
| InChIKey |
QDUBGZSEYIQVEI-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Diacylglycerol acyltransferase 1 (DGAT1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Diacylglycerol acyltransferase 1 (DGAT1) | Target's Patent Info | [1] | |
| BioCyc | Triacylglycerol biosynthesis | |||
| KEGG Pathway | Glycerolipid metabolism | |||
| Retinol metabolism | ||||
| Metabolic pathways | ||||
| Fat digestion and absorption | ||||
| Pathwhiz Pathway | Retinol Metabolism | |||
| Reactome | Acyl chain remodeling of DAG and TAG | |||
| Triglyceride Biosynthesis | ||||
| WikiPathways | Vitamin A and Carotenoid Metabolism | |||
| Statin Pathway | ||||
| Triacylglyceride Synthesis | ||||
| Glycerophospholipid biosynthesis | ||||
| Fatty acid, triacylglycerol, and ketone body metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.