Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0F7FX
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| Former ID |
DCL000062
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| Drug Name |
AZD-9684
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| Synonyms |
Laudanosine; DL-Laudanosine; 1699-51-0; (+-)-Laudanosine; Laudanosine (R,S); (R,S)-Laudanosine; EINECS 216-923-9; NSC 94267; AI3-61890; 20412-65-1; NSC35045; 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (+-)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinoline; 1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYL-1-VERATRYL-, (+-)-
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| Drug Type |
Small molecular drug
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| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Discontinued in Phase 2 | [1] | |
| Company |
AstraZeneca
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| Structure |
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Download2D MOL |
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| Formula |
C10H14N2O2S
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| Canonical SMILES |
CC(C(CC1=CN=C(C=C1)N)C(=O)O)S
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| InChI |
1S/C10H14N2O2S/c1-6(15)8(10(13)14)4-7-2-3-9(11)12-5-7/h2-3,5-6,8,15H,4H2,1H3,(H2,11,12)(H,13,14)/t6-,8-/m1/s1
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| InChIKey |
GYIYAOUGKJSCCG-HTRCEHHLSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID |
92363, 399634, 459197, 3134993, 3715869, 5338659, 8138172, 8161679, 10321374, 10512897, 11341359, 11361542, 11363757, 11366319, 11368881, 11370964, 11374626, 11377043, 11466619, 11467739, 11484461, 11486417, 11486944, 11488479, 11489928, 11492749, 11494677, 15423389, 26680393, 26754143, 29204322, 29283496, 47365460, 47440553, 47662547, 47885662, 47960017, 48185246, 48185247, 48463331, 49698825, 49747919, 49986969, 50267717, 56242095, 57329048, 85787872, 88771139, 92125428, 93576858
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018349) | |||
| REF 2 | Clinical pipeline report, company report or official report of AstraZeneca. | |||
| REF 3 | Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosine. Anesthesiology. 2001 Apr;94(4):643-51. | |||
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