Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0F7NT
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| Former ID |
DIB008633
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| Drug Name |
349U85.HCL
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| Synonyms |
6-Piperidinoquinolin-2(1H)-one hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Cardiovascular disease [ICD-11: BA00-BE2Z; ICD-10: I00-I99] | Phase 1 | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H17ClN2O
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| Canonical SMILES |
C1CCN(CC1)C2=CC3=C(C=C2)NC(=O)C=C3.Cl
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| InChI |
1S/C14H16N2O.ClH/c17-14-7-4-11-10-12(5-6-13(11)15-14)16-8-2-1-3-9-16;/h4-7,10H,1-3,8-9H2,(H,15,17);1H
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| InChIKey |
KYTREJMWHJPVSI-UHFFFAOYSA-N
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| CAS Number |
CAS 116942-30-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3 (PDE3) | Target Info | Modulator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacokinetics and pharmacodynamics of a new cardiotonic vasodilator agent, 349U85, in normal subjects. Clin Pharmacol Ther. 1994 Jan;55(1):55-63. | |||
| REF 2 | Cardiovascular pharmacology of the vasodilator-cardiotonic agent, 349U85. J Cardiovasc Pharmacol. 1992 Oct;20(4):579-89. | |||
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