Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0F8PG
|
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| Drug Name |
PMID29334795-Compound-21
|
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| Drug Type |
Small molecular drug
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| Indication | Corticobasal degeneration [ICD-11: 8A00.1Y] | Patented | [1] | |
| Progressive supranuclear palsy [ICD-11: 8A00.10; ICD-10: G23.1] | Patented | [1] | ||
| Company |
SANOFSANOFI LANGEVIN, Beverly C. FARR, Robert Allan SHAH, Dinubhai H. SHERER, DanieSANOFI-AVENTIS DIAZ MARTIN, Juan Antonio JIMENEZ BARGUENO, Maria Dolores
|
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| Structure |
 |
Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | . | [1] |
| Target's Patent Info | Histamine H3 receptor (H3R) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Progress in the development of histamine H3 receptor antagonists/inverse agonists: a patent review (2013-2017).Expert Opin Ther Pat. 2018 Mar;28(3):175-196. | |||
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