Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0F9KI
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| Former ID |
DIB000335
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| Drug Name |
LAS-30538
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| Synonyms |
Las 30538; Las-30538; 145067-04-5; AC1L31FQ; DTXSID60162875; 1-(2-(2,6-Dimethylphenoxy)ethyl)-alpha,alpha-bis-(p-fluorophenyl)-4-piperidine methanol; 4-Piperidinemethanol, 1-(2-(2,6-dimethylphenoxy)ethyl)-alpha,alpha-bis(4-fluorophenyl)-
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| Drug Type |
Small molecular drug
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| Indication | Hyperinsulinemia [ICD-11: 5A4Y] | Terminated | [1] | |
| Company |
Almirall Prodesfarma SA
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| Structure |
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Download2D MOL |
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| Formula |
C28H31F2NO2
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| Canonical SMILES |
CC1=C(C(=CC=C1)C)OCCN2CCC(CC2)C(C3=CC=C(C=C3)F)(C4=CC=C(C=C4)F)O
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| InChI |
1S/C28H31F2NO2/c1-20-4-3-5-21(2)27(20)33-19-18-31-16-14-24(15-17-31)28(32,22-6-10-25(29)11-7-22)23-8-12-26(30)13-9-23/h3-13,24,32H,14-19H2,1-2H3
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| InChIKey |
BIZCZAJFIUSFDU-UHFFFAOYSA-N
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| CAS Number |
CAS 145067-04-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The calcium channel blocker LAS 30538, unlike nifedipine, verapamil, diltiazem or flunarizine, potently inhibits insulin secretion in-vivo in rats and dogs. J Pharm Pharmacol. 1992 Oct;44(10):851-5. | |||
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