Drug Information
Drug General Information | Top | |||
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Drug ID |
D0FK6T
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Former ID |
DNC004855
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Drug Name |
2-(4-Cyclopentyl-piperazin-1-yl)-quinoline
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Synonyms |
CHEMBL178608; 2-(4-Cyclopentyl-piperazin-1-yl)-quinoline; SCHEMBL3970736
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H23N3
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Canonical SMILES |
C1CCC(C1)N2CCN(CC2)C3=NC4=CC=CC=C4C=C3
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InChI |
1S/C18H23N3/c1-4-8-17-15(5-1)9-10-18(19-17)21-13-11-20(12-14-21)16-6-2-3-7-16/h1,4-5,8-10,16H,2-3,6-7,11-14H2
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InChIKey |
JGCMOVVEQUHZRT-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Histamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Monoamine Transport | |||
GPCRs, Class A Rhodopsin-like | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | 2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists. J Med Chem. 2005 Jan 13;48(1):306-11. |
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