Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FU7Y
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| Former ID |
DNC003602
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| Drug Name |
2-Hydroxycarbamoylmethyl-pentanedioic acid
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| Synonyms |
CHEMBL65043; hydroxamate, 41; 2-Hydroxycarbamoylmethyl-pentanedioic acid; SCHEMBL1373534; BDBM17779; 2-[(hydroxycarbamoyl)methyl]pentanedioic acid; 2-[2-Oxo-2-(hydroxyamino)ethyl]pentanedioic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H11NO6
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| Canonical SMILES |
C(CC(=O)O)C(CC(=O)NO)C(=O)O
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| InChI |
1S/C7H11NO6/c9-5(8-14)3-4(7(12)13)1-2-6(10)11/h4,14H,1-3H2,(H,8,9)(H,10,11)(H,12,13)
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| InChIKey |
PILHIJIJVLWKNF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of hydroxamate-Based inhibitors of glutamate carboxypeptidase II. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2097-100. | |||
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