Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G0LH
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| Former ID |
DIB017032
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| Drug Name |
S-312-d
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| Synonyms |
S-312; S-830312
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| Drug Type |
Small molecular drug
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| Indication | Epilepsy [ICD-11: 8A60-8A68] | Discontinued in Phase 2 | [1] | |
| Company |
Shionogi & Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H22N2O4S
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| Canonical SMILES |
CC1=C(C(C2=C(N1)SC=C2CC(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
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| InChI |
1S/C20H22N2O4S/c1-11(2)8-14-10-27-19-18(14)17(16(12(3)21-19)20(23)26-4)13-6-5-7-15(9-13)22(24)25/h5-7,9-11,17,21H,8H2,1-4H3/t17-/m0/s1
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| InChIKey |
UTLPUICHKZBRCI-KRWDZBQOSA-N
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| CAS Number |
CAS 120056-57-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Blocker | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002235) | |||
| REF 2 | Protective effects of a selective L-type voltage-sensitive calcium channel blocker, S-312-d, on neuronal cell death. Biochem Pharmacol. 2004 Mar 15;67(6):1153-65. | |||
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