Drug Information
Drug General Information | Top | |||
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Drug ID |
D0G3SZ
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Former ID |
DNC011369
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Drug Name |
ALTENUSIN
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Synonyms |
AC1L4N6W; AC1Q68NU; SCHEMBL16971034; 4',5'-dihydroxy-5-methoxy-2'-methylbiphenyl-2-carboperoxoic acid; ACM31186126; J-018273; 2-(4,5-dihydroxy-2-methylphenyl)-4-methoxybenzenecarboperoxoic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H14O6
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Canonical SMILES |
CC1=CC(=C(C=C1C2=C(C(=CC(=C2)OC)O)C(=O)O)O)O
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InChI |
1S/C15H14O6/c1-7-3-11(16)12(17)6-9(7)10-4-8(21-2)5-13(18)14(10)15(19)20/h3-6,16-18H,1-2H3,(H,19,20)
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InChIKey |
ADPBTBPPIIKLEH-UHFFFAOYSA-N
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CAS Number |
CAS 31186-12-6
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PubChem Compound ID | ||||
ChEBI ID |
CHEBI:141340
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Target and Pathway | Top | |||
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Target(s) | Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) | Target Info | Inhibitor | [1] |
KEGG Pathway | PI3K-Akt signaling pathway | |||
MicroRNAs in cancer | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | Apoptosis signaling pathway | |||
CCKR signaling map ST | ||||
Pathway Interaction Database | E2F transcription factor network | |||
Direct p53 effectors | ||||
IL6-mediated signaling events | ||||
HIF-1-alpha transcription factor network | ||||
WikiPathways | Apoptosis | |||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in leukocytes - TarBase | ||||
Apoptosis Modulation and Signaling |
References | Top | |||
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REF 1 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. |
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