Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G5EI
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| Drug Name |
Indoline derivative 11
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| Synonyms |
PMID27646439-Compound-19
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| Drug Type |
Small molecular drug
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| Company |
JANSSEN PHARMACEUTICA NV
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H23BrN6O3
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| Canonical SMILES |
CN1C(=C(C=N1)Br)CC(=O)N2CCC3=C2C=CC(=C3)NC4=NC=NC5=CC(=C(C=C54)OC)OC
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| InChI |
1S/C24H23BrN6O3/c1-30-20(17(25)12-28-30)11-23(32)31-7-6-14-8-15(4-5-19(14)31)29-24-16-9-21(33-2)22(34-3)10-18(16)26-13-27-24/h4-5,8-10,12-13H,6-7,11H2,1-3H3,(H,26,27,29)
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| InChIKey |
KVVYJCRBQJOKHQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PRKR-like endoplasmic reticulum kinase (PERK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | PRKR-like endoplasmic reticulum kinase (PERK) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Jan;27(1):37-48. | |||
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