Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0GB3P
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| Drug Name |
Pyridazin-3(2H)-one derivative 1
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| Synonyms |
PMID29334795-Compound-20
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| Drug Type |
Small molecular drug
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| Company |
CEPHALON, INC. BIERLMAIER, Stephen HALTIWANGER, Ralph, Curtis JACOBS, Martin, JCEPHALON, INC. HUDKINS, Robert, L. JOSEF, Kurt, A. TAO, Ming BECKNELL, Nadine, C. HOSTETLER, Greg KNUTSON, Lars, J., S. ZULLI, Allison, L
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| Structure |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inverse agonist | [1] |
| Target's Patent Info | Histamine H3 receptor (H3R) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Progress in the development of histamine H3 receptor antagonists/inverse agonists: a patent review (2013-2017).Expert Opin Ther Pat. 2018 Mar;28(3):175-196. | |||
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