Drug Information
Drug General Information | Top | |||
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Drug ID |
D0GM9E
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Former ID |
DIB014696
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Drug Name |
RQ-00310941
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Synonyms |
RQ-00202065; 5-HT 2b antagonists (oral, IBS), RaQualia; 5-HT 2b antagonists (oral, irritable bowel syndrome), RaQualia
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Indication | Irritable bowel syndrome [ICD-11: DD91.0; ICD-10: K55-K64, K58; ICD-9: 564.1, 787.91] | Investigative | [1] | |
Company |
RaQualia Pharma Inc
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2B receptor (HTR2B) | Target Info | Antagonist | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 7). |
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