Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GY1Y
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| Former ID |
DIB010988
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| Drug Name |
CS-8080
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| Synonyms |
Liver X receptor modulator (artherosclerosis), Daiichi Sankyo Inc; LXR modulator (anti-arteriosclerotic), Daiichi Sankyo Inc
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| Indication | Arteriosclerosis [ICD-11: BD40; ICD-10: I70] | Phase 1 | [1] | |
| Company |
Daiichi Sankyo Inc
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| Structure |
 |
Download2D MOL
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| Formula |
C61H99ClN2O4
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| Canonical SMILES |
CCCCCCCCCCCCCCCCCCN1C2=CC=CC=C2C(C1=CC=CC=CC3=[N+](C4=CC=CC=C4C3(C)C)CCCCCCCCCCCCCCCCCC)(C)C.[O-]Cl(=O)(=O)=O
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| InChI |
1S/C61H99N2.ClHO4/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-44-52-62-56-48-42-40-46-54(56)60(3,4)58(62)50-38-37-39-51-59-61(5,6)55-47-41-43-49-57(55)63(59)53-45-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2;2-1(3,4)5/h37-43,46-51H,7-36,44-45,52-53H2,1-6H3;(H,2,3,4,5)/q+1;/p-1
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| InChIKey |
ZQSBJPAQPRVNHU-UHFFFAOYSA-M
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| CAS Number |
CAS 127274-91-3
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:52027
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Oxysterols receptor LXR (NR1H) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00796575) Effects of Multiple Doses of CS-8080 in Healthy Volunteers. U.S. National Institutes of Health. | |||
| REF 2 | Liver X receptors in lipid metabolism: opportunities for drug discovery. Nat Rev Drug Discov. 2014 Jun;13(6):433-44. | |||
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