Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0GY4V
|
|||
| Former ID |
DIB005406
|
|||
| Drug Name |
TY-11345
|
|||
| Synonyms |
TY 11345; (+-)-2-((4-Methoxy-6,7,8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole sodium salt; 5H-Cyclohepta(b)pyridine, 9-(1H-benzimidazol-2-ylsulfinyl)-6,7,8,9-tetrahydro-4-methoxy-, sodium salt
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Peptic ulcer [ICD-11: DA61] | Discontinued in Phase 2 | [1] | |
| Company |
Toa Eiyo KK
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H20N3NaO2S
|
|||
| Canonical SMILES |
COC1=CC[N-]C2=C1CCCCC2S(=O)C3=NC4=CC=CC=C4N3.[Na+]
|
|||
| InChI |
1S/C18H20N3O2S.Na/c1-23-15-10-11-19-17-12(15)6-2-5-9-16(17)24(22)18-20-13-7-3-4-8-14(13)21-18;/h3-4,7-8,10,16H,2,5-6,9,11H2,1H3,(H,20,21);/q-1;+1
|
|||
| InChIKey |
IPAJARTUAXFVLF-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 137927-14-1
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gastric H(+)/K(+) ATPase (Proton pump) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001313) | |||
| REF 2 | Biochemical and pharmacological properties of a newly synthesized proton pump (H+/K(+)-ATPase) inhibitor, TY-11345 in experimental animals. Jpn J Pharmacol. 1993 Aug;62(4):363-71. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.