Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H1BQ
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| Drug Name |
PMID27539678-Compound-14
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| Drug Type |
Small molecular drug
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| Company |
AJINOMOTO CO., INC
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| Structure |
 |
Download2D MOL |
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| Formula |
C28H32N2O2
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| Canonical SMILES |
CC1(CCC(=O)C(=C1)C2=CC=CC(=C2)C3=CC4=C(C=C3)NC(=C4)CN5CCCC5CO)C
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| InChI |
1S/C28H32N2O2/c1-28(2)11-10-27(32)25(16-28)21-6-3-5-19(13-21)20-8-9-26-22(14-20)15-23(29-26)17-30-12-4-7-24(30)18-31/h3,5-6,8-9,13-16,24,29,31H,4,7,10-12,17-18H2,1-2H3/t24-/m1/s1
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| InChIKey |
PNODTUCQTPQANY-XMMPIXPASA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine kinase 1 (SPHK1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine kinase 1 (SPHK1) | Target's Patent Info | [1] | |
| BioCyc | Sphingosine and sphingosine-1-phosphate metabolism | |||
| KEGG Pathway | Sphingolipid metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| VEGF signaling pathway | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Tuberculosis | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Panther Pathway | Angiogenesis | |||
| VEGF signaling pathway | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | |||
| Beta3 integrin cell surface interactions | ||||
| S1P1 pathway | ||||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| PDGFR-beta signaling pathway | ||||
| Reactome | Sphingolipid de novo biosynthesis | |||
| VEGFR2 mediated cell proliferation | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Protein folding | ||||
| Sphingolipid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Sphingosine kinase inhibitors: a review of patent literature (2006-2015).Expert Opin Ther Pat. 2016 Dec;26(12):1409-1416. | |||
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