Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H1FV
|
|||
| Former ID |
DNC001319
|
|||
| Drug Name |
Selfotel
|
|||
| Synonyms |
Selfotel; 110347-85-8; CGS 19755; CGS-19755; Selfotel [USAN:INN]; CPDD 0027; (2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid; UNII-N0905W44Y3; H-4-Pal-OH.2HCl; cis-4-(Phosphonomethyl)pipecolic acid; CHEMBL39664; 2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, cis-; CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID; CHEBI:34973; 2-Piperidinecarboxylic acid, 4-(phosphonomethyl)-, (2S,4R)-; N0905W44Y3; 113229-62-2; cis-4-(phosphonomethyl)piperidine-2-carboxylic acid; Selfotel, (+)-
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Discontinued in Phase 3 | [1], [2] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C7H14NO5P
|
|||
| Canonical SMILES |
C1CNC(CC1CP(=O)(O)O)C(=O)O
|
|||
| InChI |
1S/C7H14NO5P/c9-7(10)6-3-5(1-2-8-6)4-14(11,12)13/h5-6,8H,1-4H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1
|
|||
| InChIKey |
LPMRCCNDNGONCD-RITPCOANSA-N
|
|||
| CAS Number |
CAS 110347-85-8
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
586324, 7849468, 8192308, 43125263, 48332100, 50064149, 50927869, 57317036, 103213975, 103816492, 103918474, 104342919, 117626566, 128522852, 134224524, 134339375, 134340520, 135028998, 135374334, 135710050, 136897493, 137249407, 139347511, 142751928, 144204496, 152053538, 164758581, 172113712, 178100976, 179149579, 184559013, 198947479, 198963776, 223442243, 226491869, 252377780, 252378346
|
|||
| ChEBI ID |
CHEBI:34973
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Antagonist | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4155). | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001276) | |||
| REF 3 | Neuroprotective agents for the treatment of acute ischemic stroke. Curr Neurol Neurosci Rep. 2003 Jan;3(1):9-20. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.